Titlebook: Nicotine Psychopharmacology; Jack E. Henningfield,Edythe D. London,Sakire Pogun Book 2009 Springer-Verlag Berlin Heidelberg 2009 Imaging.M

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Molecular Genetics of Nicotine Metabolismposition kinetics that differ between individuals and ethnic groups. Twin studies indicate that a large part of this variance is genetic in origin, although environmental influences also contribute. The primary aim of this chapter is to review the current knowledge regarding the genetic variability

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Recognising Nicotine: The Neurobiological Basis of Nicotine Discriminationmal subjects. Investigations of the nicotine discriminative stimulus complex have contributed to our present understanding of nicotine psychopharmacology by defining the origin of its effects at specific subtypes of nicotinic receptor and the role of diverse neurotransmitter systems as mediating and

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Effects of Nicotine in Experimental Animals and Humans: An Update on Addictive Properties appears to play a major role in tobacco dependence, but the reinforcing effects of nicotine have often been difficult to demonstrate directly in controlled studies with laboratory animals or human subjects. Here we update our earlier review published in Psychopharmacology (Berl) in 2006 on findings

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Rodent Models of Nicotine Withdrawal Syndromeoking cessation treatments. They have led to an exponential increase of knowledge regarding the underlying neurobiological mechanisms of dependence and withdrawal syndrome. The human nicotine withdrawal syndrome in smoking cessation is variable and multidimensional, involving irritability, anxiety,

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