书目名称 | Next Generation Sequencing Technologies and Challenges in Sequence Assembly | 编辑 | Sara El-Metwally,Osama M. Ouda,Mohamed Helmy | 视频video | | 概述 | Focuses on challenges in next generation sequencing technologies.Challenges include sequencing errors, expensive processing and memory usage and sequencer specific errors.This book provides overview o | 丛书名称 | SpringerBriefs in Systems Biology | 图书封面 |  | 描述 | .The introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field..This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.. | 出版日期 | Book 2014 | 关键词 | challenges; genomics; next generation sequence technologies; next generation sequencing; sequence assemb | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-0715-1 | isbn_softcover | 978-1-4939-0714-4 | isbn_ebook | 978-1-4939-0715-1Series ISSN 2193-4746 Series E-ISSN 2193-4754 | issn_series | 2193-4746 | copyright | The Authors 2014 |
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