| 书目名称 | New Trends in Pharmacokinetics | | 编辑 | Aldo Rescigno,Ajit K. Thakur | | 视频video | | | 丛书名称 | NATO Science Series A: | | 图书封面 |  | | 描述 | The last decade or so has witnessed tremendous progress in methodology in the field of drug development in general and pharmacokinetics in particular. Clinical pharmacokinetics is using new tools for probing into the "black box" once being ac cessible only partly through experimental techniques and, mostly through mathemati cal and computer means. Development of computerized scanning, positron emission tomography (PET), stereoselectivity and other techniques are now enabling investi gators to have better pictures of the systems they are studying. Mathematical models through computer simulation and statistical estimation, mostly due to easy access be cause of inexpensive yet powerful personal computers, are enabling us to investigate ultrastructures and their functional connectivity in more detail. As a consequence, new hypotheses are being formed and tested in various related fields. In clinical pharmacokinetics, mostly due to mathematical modeling, more accurate interspecies scaling of pharmacokinetic parameters and dosimetry can be done now-a-days. The concept of "a human is a bigger rat" does not necessarily fly as a consequence. Pharmacokinetic concepts are becoming powerfu | | 出版日期 | Book 1991 | | 关键词 | drug; drug development; kinetics; metabolism; pharmacokinetics; pharmacology; receptor; research | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4684-8053-5 | | isbn_softcover | 978-1-4684-8055-9 | | isbn_ebook | 978-1-4684-8053-5 | | copyright | Plenum Press, New York 1991 |
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发表于 2025-3-21 17:06:24
