Titlebook: New Trends in Cancer for the 21st Century; Proceedings of the I Antonio Llombart-Bosch,Vicente Felipo Conference proceedings 2003 The Edito

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Arthropathy

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Matrix Metalloproteinases and Tumor Progression,es have shown that MMPs play an important role in the proteolytic destruction of extracellular matrix and basement membranes, thereby facilitating tumor invasion and metastasis. In addition, these enzymes may also be important in other steps of tumor evolution including neoplastic cell proliferation

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Mutated Tyrosine Kinases As Therapeutic Targets In Myeloid Leukemias,mechanism of transformation, and therapeutic targeting of two prototypic tyrosine kinase oncogenes, BCR-ABL and FLT3, associated with chronic myeloid leukemia (CML) and acute myeloid leukemia (AML), respectively. BCR-ABL is generated by the Philadelphia chromosome translocation between chromosomes 9

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RENIN

Immune-Promoted Tumor Cell Invasion and Metastasis,ne response against established tumors do not show repetitive good results. Apparently, malignant tumor cells escape immune recognition and attack through multiple molecular mechanisms. Laboratory experiments show that properly stimulated specific CD8+ T cells, some CD4+ T cells, NK cells, and macro

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AORTA

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