Titlebook: New Psychoactive Substances; Pharmacology, Clinic Hans H. Maurer,Simon D. Brandt Book 2018 Springer Nature Switzerland AG 2018 New psychoac

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Designer Benzodiazepines: Another Class of New Psychoactive Substances,of anxiety or sleep disorders at the time. However, benzodiazepines show a high potential of misuse and dependence. Although being of great value as medicines, dependence to these drugs is a concern worldwide, in part due to overprescription and easy availability. Therefore, the phenomenon of benzod

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Bioanalytical Methods for New Psychoactive Substances,drugs of abuse market. Screening, identification, and quantification in biosamples are needed in clinical and forensic toxicology settings, and these procedures are more challenging than the analysis of seized drug material because of extremely low concentrations encountered in biofluids but also du

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Patterns of Acute Toxicity Associated with New Psychoactive Substances,es (NPS), the challenges associated with gathering these data, the sources of information available and the limitations of each. It describes the data triangulation approach that can be used to combine individual, each inherently limited, data sources to help build the picture of the pattern of acut

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Wastewater Analysis for Community-Wide Drugs Use Assessment,illicit drug use. After consumption, biomarkers – drugs and their metabolites – excreted to toilets and flushed into urban sewer networks can be measured in raw wastewater samples. The quantified loads can serve as an estimate for the collective consumption of all people contributing to the wastewat

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Neuropharmacology of Synthetic Cathinones,nedioxypyrovalerone (MDPV) are potent transporter inhibitors that block neurotransmitter uptake (i.e., blockers). Regardless of molecular mechanism, all synthetic cathinones increase extracellular monoamine concentrations in the brain, thereby enhancing cell-to-cell monoamine signaling. Here, we bri