| 书目名称 | New Paradigms of Coronary Artery Disease | | 副标题 | Hibernation, Stunnin | | 编辑 | Gerd Heusch,Rainer Schulz | | 视频video | | | 图书封面 |  | | 描述 | Detailed analyses of regional myocardial blood flow, function, metabolism and morphology in ischemic and reperfused myocardium have led to the identifi cation of important phenomena, i. e. , myocardial hibernation, myocardial stun ning and ischemic preconditioning. Both the hibernating and the stunned myocardium characterize viable though dysfunctional as distinguished from necrotic tissue. With the advent of reperfusion procedures, the distinction between reversibly injured, hypofunctional myocardium from irreversibly injured, hypofunctional myocardium is of utmost clinical importance. The pathophysiological distinction of hibernating and stunned myocardium is con troversial, but reperfusion is mandatory anyway. Ischemic preconditioning is the most powerful maneuver known so far to delay infarct development. Its clinical significance has been suggested from retrospective analyses of data from patients suffering a myocardial infarction as well as from controlled PTCA studies. Whether or not preconditioning can be achieved pharmacologically in the clinical setting remains to be established. The mechanisms and signal cascade underlying myocardial hibernation, myocardial stunning a | | 出版日期 | Conference proceedings 1996 | | 关键词 | PTCA; artery; coronary artery disease; coronary heart disease; myocardial infarction | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-53793-6 | | isbn_softcover | 978-3-7985-1059-3 | | isbn_ebook | 978-3-642-53793-6 | | copyright | Springer-Verlag Berlin Heidelberg 1996 |
The information of publication is updating
|
|
发表于 2025-3-21 20:03:02
