Titlebook: New Directions for Medical Education; Problem-based Learni Henk G. Schmidt (Professor of Health Professions), Book 1989 Springer-Verlag New

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sively more so. In this field, there has for example been a growing recognition that, while biochemical signals play critical roles in regulating the behavior and fate decisions of stem cells, biology presents regulatory information to cells not only in the binary absence or presence of a given mole

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Roderick L. B. Neamecades. However, such therapies are completely reliant on the availability of appropriate donors and fraught with the risk of transmissible infection. Can recent advances in pluripotent stem cell technology alleviate these problems? We review the development of protocols used in haematopoietic differ

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John C. Sibleycades. However, such therapies are completely reliant on the availability of appropriate donors and fraught with the risk of transmissible infection. Can recent advances in pluripotent stem cell technology alleviate these problems? We review the development of protocols used in haematopoietic differ

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Henk G. Schmidtos. The first lines of human ESC (hESC) were derived by Thomson et al. in 1998. These cells can be indefinitely cultured in vitro and differentiated into different cell types. These cell lines constitute an excellent source of cells for the study of human genetics and gene expression patterns and as