Titlebook: New Aspects of Metabolism and Behaviour of Mesenchymal Cells during the Pathogenesis of Arterioscler; Under the Protectora Werner H. Hauss,

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Platelets and Atherosclerosis — Experimental and Clinical Studies — (Abstract)njury which develops into atheromatous lesions. Our in vitro studies using animal models demonstrated that activated platelets release thromboxane A. and other vasoactive substances which induce edematous changes in the arterial wall. These changes result in acute plasmal infiltration into the arter

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The Role of Type 1 Plasminogen Activator Inhibitor in the Regulation of the Fibrinolytic System of tpear to be in dynamic equilibrium, and any imbalance in them leads to an increased risk of thrombosis or the tendency to develop a bleeding diathesis (Astrup, 1958). This balance is severely disturbed in the atherosclerotic vessel wall (Balkuv-Ulutin, 1986; Breddin, 1986). Thrombosis is most likely

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The Cell Populations and other Components of the Atheromatous Lesions in Young People — A Preliminared industrialized countries of the world. In general there is a much better understanding of the advanced lesions which lead to clinical disease as compared to knowledge about the factors influencing developing plaques in young people at the cellular and chemical artery wall level. In the USA a four

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Atherogenic Factors of Blood: Desialylated LDL and Anti-LDL Autoantibodiesphically assessed coronary atherosclerosis has atherogenic properties. It has been established that atherogenicity of the serum is associated with low density lipoprotein (LDL) which differ from the LDL of healthy subjects. It was found out that atherogenic serum of patients contains anti-LDL autoan

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Participation of Leukocytes in the Development of Experimentally Induced Arteriosclerotic Lesions — as been numerously reported in both man and animal models [4–6, 13–16, 21, 24, 25, 27]. Various aspects of the possible involvement of these leukocytes in atherogenesis were discussed: e.g., the lipid-scavenging function ofmonocytes/macrophages [2, 26, 29] and their putative roles in stimulating smo

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The Value of Co-Culture Systems in Arteriosclerosis Researchts of growth of cells obtained from normal or atheromatous arteries have been studied in many details. Mass cultures or clone cultures of single cell species are, however, very artificial systems. In these cultures the cells may behave differently than in their normal environment so that efforts hav