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Titlebook: New Aspects in Hypertension Adrenoceptors; Symposium, November Martin Middeke,Heinrich Holzgreve Conference proceedings 1986 Springer-Verl

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书目名称New Aspects in Hypertension Adrenoceptors
副标题Symposium, November
编辑Martin Middeke,Heinrich Holzgreve
视频video
图书封面Titlebook: New Aspects in Hypertension Adrenoceptors; Symposium, November  Martin Middeke,Heinrich Holzgreve Conference proceedings 1986 Springer-Verl
描述This book reports on the current state of knowledge about adreno­ ceptors and their involvement in the pathogenesis and treatment of high blood pressure. This is a relatively recent and extremely excit­ ing addition to the field of hypertension research. The development of new analytical procedures, such as radio ligand-binding methods, has made it possible to identify and quantify the adrenoceptors in different tissues and in circulating blood cells. As a consequence, much new and valuable information has been obtained. An under­ standing of the role of the fJ-adrenoceptor-adenylatecyclase-cAMP system in hypertension is one such product of this new approach. Both review articles and new experimental and clinical data are included in this volume. New aspects of the distribution, identifica­ tion and regulation, and the chronopharmacology of adrenoceptors, as well as beta blockade, will be highlighted. The clinical contributions concern the normal regulation of the fJ­ adrenoceptor-adenylatecyclase-cAMP system, and how it is altered in hypertensives as a possible mechanism in the pathogenesis and maintenance of essential hypertension. With this knowledge it is be­ coming easier to e
出版日期Conference proceedings 1986
关键词blood pressure; calcium; hypertension; pharmacology; platelet; research
版次1
doihttps://doi.org/10.1007/978-3-642-71418-4
isbn_softcover978-3-642-71420-7
isbn_ebook978-3-642-71418-4
copyrightSpringer-Verlag Berlin Heidelberg 1986
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Effect of Fludrocortisone on Adrenoceptors and Free Intracellular Calcium in Man,eters of sympathetic activity and intracellular calcium concentration, which ultimately should be linked to altered cellular sodium transport [7] in normotensive volunteers, in whom a mineralocorticoid-induced blood pressure increase was evoked by oral administration of fludrocortisone.
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ood pressure. This is a relatively recent and extremely excit­ ing addition to the field of hypertension research. The development of new analytical procedures, such as radio ligand-binding methods, has made it possible to identify and quantify the adrenoceptors in different tissues and in circulati
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Peripheral Sympathoadrenal System: Transmitter Release and Distribution of Adrenoceptors,e (NA) on NA release will be described. The second part is a report on the differentiation and distribution of adrenoceptors mediating effects in sympathetically innervated tissues. The final section will be devoted to adrenoceptors in human blood vessels.
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Effects of Antihypertensive Agents on Alpha and Beta Adrenoceptors,concentrations have been taken as an index of sympathetic activity. Although numerous comparative studies of plasma catecholamines in hypertensives and normotensive controls exist, it is still a matter of controversy whether plasma noradrenaline levels are increased in essential hypertension (for a recent review see Goldstein 1983).
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Conference proceedings 1986re. This is a relatively recent and extremely excit­ ing addition to the field of hypertension research. The development of new analytical procedures, such as radio ligand-binding methods, has made it possible to identify and quantify the adrenoceptors in different tissues and in circulating blood c
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Beta Adrenoceptor Changes in Hypertension Induced by Dynamic Exercise,ous tissues, long-term exposure to .-adrenergic agonists results in an impaired .-adrenergic function. This reduced responsiveness of .-adrenoceptors was consistently found to be due to decreased receptor density and/or to a diminished activity of the adenylate cyclase-cAMP system.
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