Titlebook: New Approaches for Antifungal Drugs; Prabhavathi B. Fernandes Book 1992 Springer Science+Business Media New York 1992 drugs.pharmaceutical

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Importance of Chitin Synthesis for Fungal Growth and as a Target for Antifungal Agents,one, 1986), Natural product inhibitors of chitin synthesis, the polyoxins and the nikkomycins, have been found that inhibit the growth of fungi (Bowers et al., 1974; Dahn et al., 1976; Hagenmaier et al., 1979; Isono et al., 1967, 1969). However, both the fact that these agents have not proven to be

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,The Fungal Cell Wall — A Target For Lipopeptide Antifungal Agents,tifungal therapy, especially for life-threatening disseminated fungal infections, is not satisfactory because of limited efficacy and/or toxicity (Graybill, 1989). Second, there is an increased incidence of fungal infections attributed to the aggressive use of cancer chemotherapy, organ transplantat

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Pradimicin, A Novel Antifungal Agent, they do not normally cause infections because the host immune system protects against them. However, the number of patients who are severely immunocompromised by acquired immunodeficiency syndrome (AIDS), organ and bone marrow transplantations, and cancer chemotherapy has rapidly increased recently