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Titlebook: Neuroprotection and Neuroregeneration for Retinal Diseases; Toru Nakazawa,Yasushi Kitaoka,Takayuki Harada Book 2014 Springer Japan 2014 Ag

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Nitric Oxide Contributes to Retinal Ganglion Cell Survival Through Protein S-Nitrosylation After Optl death, survival, and gene expression. However, there are few reports on the role of protein S-nitrosylation in glaucoma. Therefore, we investigated the role of protein S-nitrosylation signaling in RGC survival after optic nerve injury.
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Axonal Degenerationrowing body of evidence that glaucoma may be correlated with Alzheimer’s disease. Autophagy impairment may be involved in neurodegenerative diseases including Alzheimer’s disease and glaucoma. Thus, the modulation of these signaling pathways will lead to a new concept of axonal protection.
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the disease mechanisms and treatments.Exhaustively reviews t.This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigme
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Antioxidative Treatment for Neuroprotection in Glaucomaired ocular blood flow in vivo and in vitro. Some population-based epidemiological studies showed that higher antioxidant intake reduced risk of glaucoma. This review focused on the present evidence that support the possibility of antioxidant neuroprotective treatment for glaucoma.
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ER Stressth, highlighting the possible mechanisms of neurodegenerative diseases, such as Alzheimer disease, amyotrophic lateral sclerosis, and Parkinson disease. This chapter introduces the involvement of ER stress in retinal cell death causing glaucoma and its therapeutic strategy.
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Neurotrophic Factorslex and their effects are still controversial, clinical trials using neurotrophins are underway for several retinal diseases. The current therapy for glaucoma is to lower intraocular pressure (IOP), but neurotrophic factors may be available for preventing IOP-independent RGC loss and future treatment of glaucoma.
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Roles of the Retinal Pigment Epithelium in Neuroprotectionina and the choroid. Given a number of studies reporting the RPE functions which serve for the retina and the choroid, it is essential to understand the physiological functions of the RPE in order to decipher disease- and age-related changes in vision.
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