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Titlebook: Neuroprotection and Neuroregeneration for Retinal Diseases; Toru Nakazawa,Yasushi Kitaoka,Takayuki Harada Book 2014 Springer Japan 2014 Ag

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Molecular Architecture of Glutamate Signaling Pathway in Glaucomatous Optic Neuropathyrious neurological diseases, including glaucomatous optic neuropathy (GON). Glutamate excitotoxicity triggered by overstimulation of .-methyl-.-aspartate (NMDA)-type glutamate receptors may contribute to retinal ganglion cell (RGC) degeneration in glaucoma and other retinal neuronal cell death in is
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ER Stress death in glaucoma have been reported to arise from intraocular pressure, dysregulation of ocular circulation, autoimmune diseases, and genetic predisposition and so on. However, its pathological mechanisms remain unclear. Recently, it is focused on the involvement of endoplasmic reticulum (ER) stre
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Axonal Degenerationd in glaucoma patients suggests that axonal degeneration may occur first, followed by sequential RGC body loss in this pathological condition. The molecular mechanism of axonal degeneration in the optic nerve is still unclear. The tumor necrosis factor injection model and the hypertensive glaucoma m
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