书目名称 | Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems | 编辑 | Monica Frega | 视频video | | 概述 | Nominated as an outstanding PhD thesis by the University of Genoa, Italy.Presents a powerful in vitro model of neuronal network dynamics.implementation of bio-hybrid microsystems for network electroph | 丛书名称 | Springer Theses | 图书封面 |  | 描述 | .The bookpresents a new, powerful model of neuronal networks, consisting of athree-dimensional neuronal culture in which 3D neuronal networks are coupled tomicro-electrode-arrays (MEAs). It discusses the main advantages of thethree-dimensional system compared to its two-dimensional counterpart, and showsthat the network dynamics, recorded during both spontaneous and stimulatedactivity, differs between the two models, with the 3D system being better ableto emulate the .in vivo. behaviour of neural networks. The book offers anextensive analysis of the system, from the theoretical background, to itsdesign and applications in neuro-pharmacological studies. Moreover, itincludes a concise yet comprehensive introduction to both 2D and 3D neuronalnetworks coupled to MEAs, and discusses the advantages, limitations andchallenges of their applications as cellular and tissue-like .in vitro. experimental model systems... | 出版日期 | Book 2016 | 关键词 | Neuronal Networks Coupled to MEAs; 3D Hippocampal Neuronal Networks; MEA for Network Electrophysiology | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-30237-9 | isbn_softcover | 978-3-319-80758-4 | isbn_ebook | 978-3-319-30237-9Series ISSN 2190-5053 Series E-ISSN 2190-5061 | issn_series | 2190-5053 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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