Titlebook: Neuromuscular Disease; Evidence and Analysi Michael Benatar Book 2006 Humana Press 2006 muscle.neurology.spinal cord

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Basic Principles of Epidemiology and Biostatisticslation without such exposure provides insight into the association between the exposure and the disease. “Validity” describes the extent to which a measurement is correct (i.e., reflects the truth). A major difficulty is that we typically do not know the truth. Ensuring validity, therefore, requires

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Lumbar Spondylosisots. Although there is no clear correlation between the nature of the underlying disease (i.e., soft vs hard disease) and the clinical symptomatology, it is useful to recognize these distinctions for the purposes of understanding the pathophysiology of lumbar spine disease because, at least in theor

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Polyneuropathyhe presence of a polyneuropathy and in terms of delineating the underlying pathophysiological process (i.e., primary axonal loss vs primary demyelination). Because nerve conduction studies only measure the activity of large fiber nerves, skin biopsy to determine the density of epidermal nerve fibers

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Vasculitic Neuropathysu’s arteritis). The nonsystemic vasculitides may affect either the central or the peripheral nervous system exclusively. In this chapter, we are concerned with the form of nonsystemic vasculitis that is confined to the peripheral nervous system as well as the systemic vasculitides in which the peri

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Guillain-Barré Syndromelination. Over the years, however, unusual variants of this syndrome have been recognized, including an axonal form. Plasmapheresis and intravenous immunoglobulin (IVIg) have become the mainstay of therapy and steroids are thought not to be beneficial.

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