| 书目名称 | Neuroepigenomics in Aging and Disease | | 编辑 | Raul Delgado-Morales | | 视频video | | | 概述 | One of the first books covering the major epigenetic changes on brain disorders throughout the entire lifespan of the patients.An invaluable reference that supplies extensive coverage of the role of a | | 丛书名称 | Advances in Experimental Medicine and Biology | | 图书封面 |  | | 描述 | Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan: from neurodevelopment/childhood (Rett Syndrome, Rubinstein-Taybi, autism), adolescence (eating disorders, drug addiction, anxiety), adulthood (depression, schizophrenia, amyotrophic lateral sclerosis, Huntington’s disease) and elderly (Alzheimer’s disease, Parkinson’s disease)..The book also covers the three major players on neuroepigenomic mechanisms: histones alterations, DNA modifications and non-coding RNAs, their roles at the molecular and cellular level and the impact of their alterations on ne | | 出版日期 | Book 2017 | | 关键词 | epigenomics; genomics; Neurodegenerative; Diseases; microRNAs; modifications; Proteomics; gene expression | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-53889-1 | | isbn_softcover | 978-3-319-85266-9 | | isbn_ebook | 978-3-319-53889-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 | | issn_series | 0065-2598 | | copyright | Springer International Publishing AG 2017 |
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发表于 2025-3-21 18:39:01
