Titlebook: Neurodevelopmental Disorders; Employing iPSC Techn Emanuel DiCicco-Bloom,James H. Millonig Book 2020 Springer Nature Switzerland AG 2020 iP

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Using Two- and Three-Dimensional Human iPSC Culture Systems to Model Psychiatric Disorders,stablished diagnostic categories, the general absence of focal pathology, and the genetic complexity inherent in these mostly polygenic disorders. Each of these features presents unique challenges to disease modeling for biological discovery, drug development, or improved diagnostics. In addition, l

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Development of a 3-D Organoid System Using Human Induced Pluripotent Stem Cells to Model Idiopathicy genes and the environment. Autism represents a spectrum in which heterogeneous genetic backgrounds are expressed with similar heterogeneity in the affected domains of communication, social interaction, and behavior. The impact of gene-environment interactions may also account for differences in un

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978-3-030-45495-1Springer Nature Switzerland AG 2020

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Emanuel DiCicco-Bloom,James H. MillonigProvides a compendium of iPSC reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders.Discusses common phenotypes and potential molecular