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Titlebook: Neuroblastoma; M.A. Hayat Book 2012 Springer Science+Business Media B.V. 2012 Childrens tumor.Diagnosis ofchildren suffering from cancer.Q

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Pediatric Neuroblastoma: Molecular Detection of Minimal Residual Diseasencluding new therapies can be accurately compared. The most commonly used and most widely evaluated marker for molecular MRD detection in neuroblastoma is the rate limiting enzyme in the catecholamine synthesis, tyrosine hydroxylase (TH). Standard operating procedures (SOPs) have been recommended fo
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A Comprehensive Tissue Microarray-Based FISH Screen of , Gene in Neuroblastomasrted disease-associated . mutations are located in the tyrosine kinase domain and the majority are thought to be drivers of an oncogenic process. However, these mutational studies are robust and are not feasible in the clinical setting especially on clinical samples of neuroblastoma. In addition, an
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Neuroblastoma: Triptolide Therapyent cell killing. In order to ascertain whether triptolide-mediated cell death occurs via an apoptotic pathway, caspase-3 and -9 activities as well as annexin staining were measured; these markers of apoptosis were found to be elevated, implicating an apoptotic pathway. As triptolide is a known inhi
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