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Titlebook: Neurobiology of Opioids; Osborne F. X. Almeida,Toni S. Shippenberg Book 1991 Springer-Verlag Berlin Heidelberg 1991 CNS.Nucleotide.Rezepto

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Distribution of Opioids in Brain and Peripheral Tissuestiple opioids were discovered almost simultaneously. The pentapeptides Met- and Leu-Enkephalin (ENK) were isolated together from brain tissue (Hughes et al. 1975) and .-endorphin (.-END) soon thereafter from pituitary extracts (Chretien et al. 1976; Li and Chung 1976). This immediately brought into
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Multiple Opioid Receptorseet event. On the one hand, it is high time to pay tribute to Albert Herz, an outstanding researcher whose laboratory has contributed enormously to the field of opiate/opioid pharmacology and who has been one of the leaders of the International Narcotic Research Conference (INRC) from its inception
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Molecular Approaches to Isolating Opioid Receptorsacological properties have since been extensively characterized (for reviews, see Iwamoto and Martin 1981; Smith and Loh 1981; Wood 1982). However, full structural and functional characterization of a receptor requires its purification and reconstitution in membrane preparations; for several reasons
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