Titlebook: Neurobiological Studies of Addiction in Chronic Pain States; Carolyn A. Fairbanks,Thomas J. Martin, Ph.D. Book 2014 Springer Science+Busin

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Carolyn A. Fairbanks,Thomas J. Martin, Ph.D.Focuses on methodological information important to the blend of chronic pain and addiction modeling.Explores current research on the specific brain regions and responses to opioids in subjects with ch

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2627-535X c brain regions and responses to opioids in subjects with chUsing rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction.978-1-4939-5183-3978-1-4939-1856-0Series ISSN 2627-535X Series E-ISSN 2627-5341

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Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Presternatives, the most effective pharmacological tools for managing diverse chronic pains remain the opioid analgesics. Several serious side effects including, the risks of addiction or diversion of opioid-containing dosage forms to nonpatient populations render the use of opioid medication for treatm

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The Influence of Pain on Reward Processing: Current Literature and Prospectsotivational drive to obtain reward, whereas the pleasure that is felt when a reward is obtained seems to be unchanged or even decreased. In addition, brain systems that are important for pain modulation as well as reward processing are altered by pain, possibly leading to less efficient endogenous p

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Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suvere noncancer pain due to other causes. However, μ-agonists also have various side-effects, in addition to potential for abuse or addiction. Recent clinical studies have shown that when μ-agonist analgesics are used appropriately to control pain, abuse and addiction usually do not develop. This cha

Charlatan

Drug Addiction and Chronic Pain: A Review of Animal Modelse development and maintenance of chronic pain conditions are especially important and have directly impacted the availability of treatments for many common pain conditions such as neuropathic, inflammatory, and visceral. The most efficacious and first choice treatment option for chronic pain is opio

insipid

Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and S addiction. The class of opioid analgesic compounds and pharmaceutical dosage forms include not only chemicals with similar characteristics but also some significant distinctions that can impact the ultimate pharmacological effects on both analgesia and potential for addiction. In developing and/or

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Prenatal Exposure to Opioids young and women in comparison to more traditional abused opioids like heroin. The changing demographics of opioid abuse are leading to rises in neonatal narcotic abstinence syndromes (NNAS), which can require substantial hospitalization. In addition to NNAS there can be long-term effects on health

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Opioids in an Evidence-Based Worldstitute of Medicine estimated that 100 million American adults are affected by chronic pain of any type and that associated costs (including lost productivity) are as high as $635 billion [1]. Pain is also an expected outcome of surgery. In 2010, 51.4 million inpatient surgical procedures were perfo