Titlebook: Neuroanatomy and Pathology of Sporadic Parkinson‘s Disease; Heiko Braak,Kelly Del Tredici Book 2009 The Editor(s) (if applicable) and The

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Prologue, as a monosystemic disorder with preferential obliteration of dopaminergic neurons in the nigrostriatal system is inadequate because it is too narrow. The pathology is widely distributed throughout the entire nervous system, not only the central (CNS) but also the peripheral (PNS) and enteric nervou

小口啜饮

Morphology of Lewy Pathology,1992, 1998; Spill-antini et al. 1997; Baba et al. 1998; Clayton and George 1998, 1999; Lavedan 1998; Trojanowski and Lee 1998, 2000, 2003; Golbe 1999; Golbe and Mouradian 2004; Duda et al. 2000; Goldberg and Lansbury 2000; Giasson et al. 2000a, 2001; Galvin et al. 2001; Goedert 2001; Walker and LeVi

关心

安心地散步

Stage 3, entire tectum and thalamus are uninvolved (see Sect. 7.1). Slight changes are visible in the somatomotor nuclei of the eye muscles (cranial nerves III, IV, VI). Phylogenetically older components of the limbic system, such as the habenular nuclei, interpeduncular nucleus, and dorsal tegmental nucleu

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会议

Stages 5 and 6,gion, periamygdalar cortex, cortical and accessory cortical subnuclei of the amygdala show heavy involvement. With the exception of the medial subnucleus of the amygdala, all components of the olfactory system eventually become affected. Together with the temporal mesocortex, the insular, subgenual,

Corral

Erythropoietin

The Staging Hypothesis: Assumptions, Challenges, Potential,y pathology in sPD is age-related but not an inevitable concomitant of the aging process. (4) Incidental Lewy pathology found in nonsymptomatic individuals represents a premorbid state. Lesion density and individual differences in disposition, including existing comorbidities, probably determine whe

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