书目名称 | Neuroanatomy and Pathology of Sporadic Alzheimer‘s Disease |
编辑 | Heiko Braak,Kelly Del Tredici |
视频video | |
概述 | Written by experts in the field of Alzheimer‘s disease.Provides excellent anatomical and pathological basis for researchers working with experimental and molecular-biological aspects of Alzheimer‘s di |
丛书名称 | Advances in Anatomy, Embryology and Cell Biology |
图书封面 |  |
描述 | As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail |
出版日期 | Book 2015 |
关键词 | amyloid precursor protein; argyophilic lesions; neurofibrillary changes; non-Alzheimer disorder; plaque- |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-319-12679-1 |
isbn_softcover | 978-3-319-12678-4 |
isbn_ebook | 978-3-319-12679-1Series ISSN 0301-5556 Series E-ISSN 2192-7065 |
issn_series | 0301-5556 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |