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Titlebook: Nephrocalcinosis Calcium Antagonists and Kidney; Karl-Horst Bichler (Medical Director),Walter Ludwi Book 1988 Springer-Verlag Berlin Heide

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https://doi.org/10.1007/978-3-642-72857-0calcium; kidney; metabolism; morphology; pharmacodynamics; research; transplantation
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Ca2+ Antagonists — Mode of Action and Pharmacodynamicsrm Ca. antagonist (or Ca. entry blocker or slow channel blocker) is being used for a whole group of substances which basically have the same mode of action despite their heterogenous chemical structure [31]. The group of Ca. antagonists comprises
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Pathological Anatomy, Etiology, and Pathogenesis of Nephrocalcinosisf view; only a few fundamental light and electron microscopic studies are available (Randall and Melvin 1937; Jaccottet 1957; Caulfield and Schrag 1964; Anderson 1982), but the physiology and pathophysiology of the renal handling of calcium have evoked increasing interest.
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Nephron- and Collecting Duct Structure in the Kidney, RatThe rat kidney is a unipapillary kidney. In histologic sections the different regions of this kidney are well discernible, since the tubules as well as the blood vessels are arranged in a regular zonal pattern. The renal cortex, as a whole, is cup-shaped, with inverted margins, and surrounds the renal medulla.
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Clinical Aspects of NephrocalcinosisThe term nephrocalcinosis was coined by Albright et al. [1] to describe the calcium deposits found in the kidneys in hyperparathyroidism. It is distinct from nephrolithiasis, or stones in the pelvicalyceal system, though the two conditions frequently coexist.
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or a number of years. Less well known, in contrast, is the effect this group of substances has on the kidneys, both on kidney cells and the blood flow through the kidneys. This effect was the subject of a workshop we organized in Tiibingen in June 1986. Different groups studied the effects of these
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Cellular Mechanisms of Renal Calcium Transport) by 10–20%. Accordingly, the ratio TF/UF approaches 1.1–1.2. In later portions of the proximal tubule calcium reabsorption parallels fluid reabsorption and TF/UF remains constant [1, 14, 17–19, 32, 46, 50, 53].
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