书目名称 | Neoplastic Transformation in Human Cell Culture | 副标题 | Mechanisms of Carcin | 编辑 | Johng S. Rhim,Anatoly Dritschilo | 视频video | | 丛书名称 | Experimental Biology and Medicine | 图书封面 |  | 描述 | The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 spea | 出版日期 | Book 1991 | 关键词 | Activation; DNA; aging; cancer; cancer research; carcinogenesis; carcinoma; cell; cell culture; mutation; onco | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4612-0411-4 | isbn_softcover | 978-1-4612-6750-8 | isbn_ebook | 978-1-4612-0411-4 | copyright | Springer Science+Business Media New York 1991 |
The information of publication is updating
|
|