Titlebook: Neonatal Immunity; Constantin Bona Book 2005 Humana Press 2005 Antigen.autoimmune disease.cytokine.diseases.vaccine

Acquired

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CLAP

Antibody Responses in Fetuses and Newborns,orn lymphocytes was derived from an experiment carried out in mice. This experiment showed that newborn mice injected with high numbers of allogeneic hematopoietic cells failed to reject the allograft ..

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Neonatal Autoimmune Diseases Caused by Maternal Pathogenic Autoantibodies,or -independent foreign antigens leads to production of antibodies with exquisite specificity for epitopes born by a large complement of foreign antigens. However, B cells can produce antibodies that display activity to self-antigens. Self-reactive antibodies are classified in three major categories

GNAT

Phenotypic Characteristics of Neonatal T Cells,n-specific cell-mediated immunity (CMI) response, and exhibit regulatory properties that modulate the function of antigen-presenting cells (APCs), B cells, and various subsets of T cells. By virtue of secretion of cytokines, T cells also modulate the function of nonlymphoid somatic cells.

INCUR

Expression of MHC Molecules in Neonates,g cells (APCs) in association with major histocompatibility complex (MHC) molecules. Therefore, the expression of MHC molecules on APCs and the ability of APCs to process the antigens play a crucial role in the activation of T cells, which are the effectors of cell-mediated immunity (CMI).

跟随

Cell-Mediated Immune Responses in Neonates,fectors of delayed-type hypersensitivity reactions, producing cytokines such as IFN-γ, which activates macrophage to kill obligatory intracellular pathogens, and interleukin (IL)-2, which promotes the growth of CD8 T cells. Th1 cells also promote class switching of IgM to IgG2. Th2 cells secrete cyt

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Fetal and Neonatal Tolerance,is able to recognize an entire complement of foreign and self-antigens estimated between 100 billion and 100 quadrillion different structures. However, in adult life the immune system does not struggle to distinguish between self-and non-self-antigens, because it learned this distinction during onto

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