| 书目名称 | Natural Resistance to Tumors and Viruses | | 编辑 | Otto Haller | | 视频video | | | 丛书名称 | Current Topics in Microbiology and Immunology | | 图书封面 |  | | 描述 | Natural resistance is now coming to be recognized as a potentially important phenomenon in host defense against infection and ma lignancy. Genetically controlled resistance mechanisms are usUally effective early in infection and before conventional immune responses are generated. Comparisons of experimental systems where natural resistance plays a prominent role demon strate the complexities of the host defense mechanisms involved, as evidenced in the present volume. Nevertheless, some com mon components of genetic resistance are discernible and largely comprise natural killer cells, macrophages, and interferon These and additional factors would seem to constitute a first line of de fense in host resistance against both viruses and tumors. It is evi dent that considerable variation in the relative importance of di stinct mechanisms may be found among various resistance sy stems and that, most likely, additional effector functions will be discovered. Resistance to tumors and most viruses is under polygenic control, has a complex mode of inheritance, and depends on appro priately complex effector mechanisms. Instances, however, whe re a single gene locus determines resistanc | | 出版日期 | Book 1981 | | 关键词 | Killer cells; Resistance; interferon; interferon research; macrophages | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-68069-4 | | isbn_softcover | 978-3-642-68071-7 | | isbn_ebook | 978-3-642-68069-4Series ISSN 0070-217X Series E-ISSN 2196-9965 | | issn_series | 0070-217X | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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发表于 2025-3-21 16:29:45
