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Titlebook: Narcotic Drugs; Biochemical Pharmaco Doris H. Clouet Book 1971 Plenum Press, New York 1971 Calcium.DNA.RNA.amino acid.bacteria.biochemistry

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楼主: Tyler
发表于 2025-3-30 10:59:16 | 显示全部楼层
Methods of Chemical Analysisal methods for identification are obviously applicable to all compounds possessing the properties, or combination thereof, upon which the analysis is based. Therefore, evaluation of the specificity of the analysis for a given compound is of utmost importance.
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发表于 2025-3-30 17:38:18 | 显示全部楼层
Peripheral Tissues the passage of a charcoal meal through the intestine. Transection of the spinal cord between C4 and L4 had no effect on this constipating action, indicating that morphine acted at a site above the fourth cervical vertebra..
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Structure-Activity Relationshipsmal test procedures then in use.. The importance of this finding lies in the fact that the narcotic-antagonist analgesics have a much lessened abuse potential. They do not produce a typical morphine-like physical dependence..
发表于 2025-3-31 06:29:50 | 显示全部楼层
Catecholamines and 5-Hydroxytryptamines neurotransmitters. While their functions in the CNS are not nearly as clearly defined, it appears reasonable to make inferences by analogy and, despite the gaps, attempt to utilize the existing knowledge of the biogenic amines as a framework for explaining morphine effects.
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Acetylcholine and Cholinesterasepressants methylpentynol and pentobarbitone. A similar rise in brain acetylcholine also was obtained with levorphan but not with norlevorphan or levallorphan.. The latter pair of drugs produced neither analgesia nor depression in rats in the doses used.
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发表于 2025-3-31 19:35:51 | 显示全部楼层
Biotransformationsdy of the metabolism of the parent drug, and (4) the biotransformation usually converts a lipid-soluble drug to a more water-soluble catabolite, thus easing and hastening the elimination of the drug from the body.
发表于 2025-3-31 22:42:28 | 显示全部楼层
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