| 书目名称 | Molecular Pathology of Breast Cancer |
| 编辑 | Sunil Badve,Yesim Gökmen-Polar |
| 视频video | |
| 概述 | Desktop ready reckoner to one and all interested in breast cancer.An overview detailing the most recent advances in the molecular pathology of breast cancer to satisfy the requirements of a diverse gr |
| 图书封面 |  |
| 描述 | .The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. ..The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in |
| 出版日期 | Book 2016 |
| 关键词 | Breast Cancer; Molecular markers; Biomarkers; Pathobiology; Precision medicine |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-41761-5 |
| isbn_softcover | 978-3-319-82422-2 |
| isbn_ebook | 978-3-319-41761-5 |
| copyright | Springer International Publishing Switzerland 2016 |
发表于 2025-3-21 16:56:34
