书目名称 | Molecular Mechanisms for Repair of DNA | 副标题 | Part A | 编辑 | Philip C. Hanawalt,Richard B. Setlow | 视频video | | 丛书名称 | Basic Life Sciences | 图书封面 |  | 描述 | An "age" has passed in the 40 years since we first observed recovery from radiation damage in irradiated bacteria. During the early 1930s, we had been discussing the possibility of rapid changes after radiation exposure with Farring ton Daniels, Benjamin Duggar, John Curtis, and others at the University of Wisconsin. After working with living cells, we had concluded that organisms receiving massive insults must have a wide variety of repair mechanisms available for restoration of at least some of the essential properties of the cell. The problem was how to fmd and identify these recovery phenomena. At that time I was working on a problem considered to be of great importance-the existence of the so-called mitogenetic rays. Several hundred articles and a score of books had already appeared dealing with mitogenetic rays, a type of radiation that was thought to exist in the shorter ultraviolet region. Our search for mitogenetic rays necessitated the design of experiments of greatest sensitivity for the detection of ultraviolet. It was vital that conditions be kept as constant as possible during exposure. All the work was done at icewater temperature (3-5°C) during and after exposure. | 出版日期 | Book 1975 | 关键词 | Activation; Mammalia; Recovery; bacteria; cell; cells; experiment; molecular mechanisms; radiation; temperatu | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4684-2895-7 | isbn_softcover | 978-1-4684-2897-1 | isbn_ebook | 978-1-4684-2895-7 | copyright | Springer Science+Business Media New York 1975 |
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