Titlebook: Microglia; Physiology, Pathophy Marie-Ève Tremblay,Alexei Verkhratsky Book 2024 The Editor(s) (if applicable) and The Author(s), under excl

小母马

Receptors on Microgliaitage and newly acquired neural specialisation. Microglia possess, depending on the particular context, receptors to neurotransmitters and neuromodulators as well as immunocompetent receptors. This rich complement allows microglial cells to monitor the functional status of the nervous system, contri

motor-unit

Calcium Signalling in Microgliaa. concentration ([Ca.].) are generated in response to physiological and pathological stimuli. Parameters of these intracellular Ca. signals are defined by Ca. signalling toolkits that may change with age or context therefore increasing adaptive capabilities of microglia. Main Ca. signalling pathway

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Noisome

Microglia Colonization Associated with Angiogenesis and Neural Cell Developmentoliferation, differentiation, and neurovascularization. As microglia colonize and establish within the developing nervous system, they assume a neural-specific identity and contribute to key developmental events. Their association around blood vessels implicates them in development of the vascular s

Allure

百灵鸟

Microglial Modulation of Synaptic Maturation, Activity, and Plasticityxperimental evidence that microglia modulate neuronal and synaptic activity during normal development and in adults. We show that microglia can regulate the maturation and function of both inhibitory and excitatory synapses that can be stimulated or repressed. We further review the fact that these r

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Microglial Regulation of Sleep and Wakefulnessaracterized, it is increasingly recognized that neurons are not the sole conductor orchestrating the rhythmic cycle of sleep and wakefulness. In the central nervous system, microglia have emerged as an important player in sleep regulation. Within the last two decades, microglia have gained substanti

火海

Roles in Innate Immunityy roles during the initiation, propagation, and resolution of inflammation. The discovery of resident adaptive immune cells in the CNS has unveiled a relationship between microglia and adaptive immune cells for CNS immune-surveillance during health and disease. The interaction of microglia with elem