Titlebook: Microglia; Methods and Protocol Olga Garaschuk,Alexei Verkhratsky Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2

臆断

Electrophysiological Investigation of Microgliahese channels whose expression varies largely in pathological conditions but also during normal development and aging. This chapter focuses on protocols allowing the recording and the analysis of these channels in acute brain slices, with a particular emphasis on the study of channels activated by extracellular ligands.

走调

土产

Microglia: The Neural Cells of Nonneural Originc stripping and phagocytosis of redundant neurons; microglia also secrete neuroactive factors regulating synaptic transmission. Novel techniques emerging in recent decade allowed an in-depth understanding of physiological and pathophysiological functions of microglia.

cunning

Microglia Reactivity: Heterogeneous Pathological Phenotypesccount the exquisite reactivity of these immune cells to changes occurring in the CNS in both physiological and pathological conditions. We briefly review here the results and methods that have uncovered the dynamics and versatility of microglial reactivity.

服从

Visualizing Dark Microgliaration of high-quality brain tissues for transmission electron microscopy, the imaging, the identification of dark microglia, and the ultrastructural analysis of various parameters that can be studied in these cells.

陈列

Measuring Microglial Turnover in the Adult Brain how it may contribute to the pathogenesis and/or progression of neurological disorders. Here we describe a robust immunohistochemical method to analyze microglial proliferation in mouse brain, aiming at providing a shared and universal approach to analyze microglial dynamics across different laboratories.

exhilaration

collagenase

Marie-Ève Tremblay,Ania K. Majewskaany order, the reader will benefit more from the case studies if he or she reads them together with the related techniques..The papers combine topics like modeling, benchmarking, testing, performance evaluation978-3-642-43674-1978-3-642-29032-9

使激动

Katherine Figarella,Nestor L. Uzcategui,Michael Duszenko

Breach