Titlebook: Microdialysis Techniques in Neuroscience; Giuseppe Di Giovanni,Vincenzo Di Matteo Book 2013 Springer Science+Business Media, LLC 2013 Brai

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Achieving High Temporal Resolution for In Vivo Measurements by Microdialysis,is important to improve the temporal resolution to measure fast neurochemical events that go unnoticed with slower analyses. For example, many behavioral or pharmacological studies induce neurochemical release on the timescale of seconds or less. To better understand neurotransmitter release dynamic

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Indirect Analysis of Nitric Oxide and Quantitation of Selective Nitric Oxide Synthase Inhibitors inicated that nitric oxide also is an important messenger in the central nervous system. Due to the extremely labile nature of this molecule, quantitation in bulk brain tissue is problematic. Indirect methods of analysis, therefore, have been developed, with the use of microdialysis technology for sam

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Determination of Histamine in Microdialysis Samples from the Rodent Brain by Column Liquid Chromatoin structures of experimental animals including rats and mice. In the alkaline medium, histamine reacts with .-phthalaldehyde (OPA) to form fluorescence products. This feature has been utilized for sensitive determination of histamine by HPLC with postcolumn OPA derivatization of histamine in the mi

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Intracerebral Microdialysis in the Study of Limbic Seizure Mechanisms and Antiepileptic Drug Actionf action of both old and new generation antiepileptic drugs. With the need of novel antiepileptic drugs for the high percentage of pharmacoresistant patients, microdialysis serves both as a drug delivery tool and/or sampling method which is often combined with other complementary neurotechniques in

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