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Titlebook: Microdialysis Techniques in Neuroscience; Giuseppe Di Giovanni,Vincenzo Di Matteo Book 2013 Springer Science+Business Media, LLC 2013 Brai

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发表于 2025-3-21 17:21:15 | 显示全部楼层 |阅读模式
书目名称Microdialysis Techniques in Neuroscience
编辑Giuseppe Di Giovanni,Vincenzo Di Matteo
视频video
概述Features cutting-edge approaches to studying brain neurochemistry in vivo, with regard to physiology, psychopharmacology, drug metabolism, and pathology.Includes detailed guidance and practical tips f
丛书名称Neuromethods
图书封面Titlebook: Microdialysis Techniques in Neuroscience;  Giuseppe Di Giovanni,Vincenzo Di Matteo Book 2013 Springer Science+Business Media, LLC 2013 Brai
描述.Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. .Microdialysis Techniques in Neuroscience. focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book’s contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the .Neuromethods. series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice.. .Detailed and authoritative, .Microdialysis Techniques in Neuroscience. will be a valuable reference for students, neuroscientists, and ph
出版日期Book 2013
关键词Brain function; Energy metabolism; Extrasynaptic pools; Microdialysis; Neuromodulators; Neuronal circuit
版次1
doihttps://doi.org/10.1007/978-1-62703-173-8
isbn_softcover978-1-4939-5814-6
isbn_ebook978-1-62703-173-8Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightSpringer Science+Business Media, LLC 2013
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发表于 2025-3-21 22:37:53 | 显示全部楼层
In Vivo Microdialysis to Study Striatal Dopaminergic Neurodegeneration, as it allows work with sample in vivo from freely moving animals. Different drugs in different points implanted probes in several brain areas can be infused simultaneously by means of microdialysis. Parkinson’s disease (PD) is a progressive neurodegenerative disorder that is primarily characterized
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Microdialysis and Advances for Sampling Synaptic and Extrasynaptic Pools,on, and to most processes fundamental to life for multicellular organisms. As a sampling technique microdialysis enables in vivo studies of brain and other tissues and has advanced our understanding of intercellular signal processing. The first part of this chapter is an overview of microdialysis in
发表于 2025-3-22 09:42:09 | 显示全部楼层
In Vivo Microdialysis for Measurement of Oxidative Metabolism in the Living Brain,ctive tracer is included. Upon introduction of a .C-labeled compound into the interstitial fluid of the brain, the compound is transported into cells and metabolized into various products including CO.. The .C-metabolites, including .CO. released to the interstitial fluid, equilibrate with fluid in
发表于 2025-3-22 16:26:40 | 显示全部楼层
Quantitative In Vivo Microdialysis in Pharmacokinetic Studies,have put in evidence important limitations of the usual in vivo calibration methods used in quantitative microdialysis for pharmacokinetic studies. Recovery values obtained by using the more classical methods of calibration (the variation of flow rate perfusion method, the delivery and retrodialysis
发表于 2025-3-22 20:21:30 | 显示全部楼层
Combination of In Vivo Microdialysis with Selective Electrochemical Detection for Online Continuous to form novel online analytical methods for continuously monitoring brain chemistry, without the need for sample collection, pretreatment, or separation. While efficient combination of in vivo microdialysis sampling directly with selective electrochemical detection is envisaged to provide less tech
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Monitoring Extracellular Monoamines with In Vivo Microdialysis in Awake Rats: A Practical Approach,larly in laboratories involved in neuropharmacology studies. Nevertheless, microdialysis of monoamines is a challenging technique for several reasons and to get reliable results it is necessary to develop sufficient skill and be ready to solve technical and analytical problems that may occur. This c
发表于 2025-3-23 07:52:27 | 显示全部楼层
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