Titlebook: Microbial Production of High-Value Products; Bernd H. A. Rehm,David Wibowo Book 2022 The Editor(s) (if applicable) and The Author(s), unde

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,Recent Advances in Poly-(γ-Glutamic Acid) Production by Microbial Fermentation, a promising biopolymer and has broad applications in food, medicine, agriculture, daily chemicals, and environmental protection due to its water-soluble, biodegradable, and nontoxic properties. The production of γ-PGA has already been established on an industrial scale. This chapter provides update

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Bioengineering and Bioprocessing of Virus-Like Particle Vaccines in ,e nature of VLPs, their size, and particulate form result in the capacity for effective stimulation of humoral and cellular immune responses. VLP vaccines have achieved commercial success for protection against cognate viruses. However, there is a rich field of research dedicated to harnessing the i

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Encapsulin Nanocompartments for Biomanufacturing Applications,e many scaffolds available for in vivo and cell-free applications, encapsulin protein nanocompartments have garnered recent attention due to their desirable properties as a scaffold, such as robust self-assembly, high thermal stability, and the inherent ability to package and display enzymatic cargo

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Advancements in Inducer Systems for Recombinant Protein Production in ,strength is crucial for efficient protein production. Promoter strength depends on the promoter components that can be either constitutive or inducible. Constitutive promoters allow continuous gene expression, which can cause a metabolic burden affecting cell growth, whereas inducible promoters cont

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Strategies for Improving Biotherapeutic Protein Production in Microbial Cell Factories,om clone development, cell line engineering, and process development all have a role to play in this endeavor. This chapter aims to address the topic of manufacturing biotherapeutics via microbial cell factories. Activities from cloning to upstream process development are described.

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Current Trends and Prospects in Antimicrobial Peptide Bioprocessing,nd in large-scale environments. Furthermore, different bioprocessing strategies can be used for peptide industrial production, aiming to optimize the yield, make cultures more robust and significantly increase cell density. In this chapter, we will address recent developments and future directions i

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