Titlebook: Microarray Technology and Cancer Gene Profiling; Simone Mocellin Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusiv

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书目名称Microarray Technology and Cancer Gene Profiling影响因子(影响力)




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书目名称Microarray Technology and Cancer Gene Profiling网络公开度学科排名




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书目名称Microarray Technology and Cancer Gene Profiling被引频次学科排名




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书目名称Microarray Technology and Cancer Gene Profiling年度引用学科排名




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书目名称Microarray Technology and Cancer Gene Profiling读者反馈学科排名

沙文主义

Technological Platforms for Microarray Gene Expression Profilinge. DNA microarray technology is evolving rapidly and there are now numerous high-density platforms available which differ in terms of probe content, design, deposition technology, labeling and hybridization protocols. However, two major platforms for high-density microarray manufacture are in common

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Principles of Gene Microarray Data Analysisf gene expression (SAGE), and gene microarray, together with the sequencing of the human genome, has provided an opportunity to monitor and investigate the complex cascade of molecular events leading to tumor development and progression. The availability of such large amounts of information has shif

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Gaining Weights ... and Feeling Good about It! spot quality information in inference except by all-or-nothing spot filtering. In this chapter we propose an approach based on using weights to overcome these two problems. The first approach uses weighted p-values to make inference robust to normalization and the second approach uses weighted spot

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Complementary Techniquesused for high-throughput analyses. While precise estimates of the level of DNA concentration in a given specimen is rarely studied (with the exception of relatively crude analyses of gene amplification or loss in cancer specimens), it is critical to know the proportional expression of various RNA tr

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Complementary Techniquess need to be validated with highly reliable biotechniques allowing for precise quantitation of transcriptional abundance of identified genes. Quantitative real time PCR (qrt-PCR) technology has recently reached a level of sensitivity, accuracy and practical ease that support its use as a routine bio

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Gene Profiling for the Prediction of Tumor Response to Treatmentely studied specific interactions between immune and cancer cells and have identified cofactors that may modulate the effectiveness of such interactions. In particular, as a result of the increasing molecular understanding of the basis for tumor/host interactions, their complexity has become manifes

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Identification of Molecular Determinants of Tumor Sensitivity and Resistance to Anticancer Drugsell lines selected for growth in the presence of sublethal concentrations of various anticancer drugs. They involve drug transport and detoxification, qualitative or quantitative alterations of the drug target, repair of drug-induced DNA lesions, and alterations in signaling or execution of apoptosi