Titlebook: MicroRNAs in Cancer Translational Research; William C.S. Cho Book 2011 Springer Science+Business Media B.V. 2011 Cancer.Oncology.Translati

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MicroRNAs in Leukemia,As) have the ability to function as both tumor suppressor and oncogene. Microarray-based miRNA expression profiling has been performed for different leukemias and can identify leukemia subtypes and prognostic classification. Specific expression patterns also suggest that miRNAs contribute to leukemo

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MicroRNAs in Pancreatic Cancer: Potential Interests as Biomarkers and Therapeutic Tools,ck of early diagnostic markers and efficient therapeutic treatments. PDAC does not appear de novo but rather originates of an accumulation of genetic and epigenetic alterations that leads to an aberrant production of diverse molecules such as RNA and proteins. These altered expression profiles resul

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MicroRNAs in Brain Tumors,py is primarily based on diagnostic histopathology, it is increasingly clear that tumors with similar or indistinguishable histologies can exhibit substantial molecular heterogeneity that dictate clinical phenotypes. Recent whole genome studies indicate molecular diversity of brain tumors not only r

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MicroRNAs in Cancer Invasion and Metastasis,elopment. One area that is currently receiving much attention is that of microRNAs (miRNAs). The miRNAs are small, non-coding molecules that inhibit gene expression post-transcriptionally, and emerging evidence suggests that miRNAs are involved in cell growth, differentiation, and apoptosis. These d

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ry material: Mankind has evolved both genetically and culturally to become a most successful and dominant species. But we are now so numerous and our technology is so p- erful that we are having major effects on the planet, its environment, and the b- sphere. For some years prophets have warned of t