Titlebook: Methods of Microarray Data Analysis II; Papers from CAMDA ’0 Simon M. Lin,Kimberly F. Johnson Book 2002 Springer Science+Business Media New

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Modeling Pharmacogenomics of the NCI-60 Anticancer Data Set: Utilizing Kernel Pls to Correlate the ugs to different cell lines (types of cancer). We have shown the efficacy of PLS in identifying drug resistant and drug sensitive genes. We have also investigated techniques to exploit the non-linear dependence between individual gene expressions in order to explain variations in the drug activity p

integrated

Evaluation of Current Methods of Testing Differential Gene expression and Beyond,tically significant differences in expression in the LE vs. RE comparison than between the OV vs. BR. The permutation works similarly to the t-test itself. Overall, the pooled variance approach proved a better strategy. For sample size, as expected, the number of significant genes increased as the n

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of analysis in each chapter. Real examples expose the strengths and weaknesses of each method for a given situation, aimed at helping readers choose appropriate protocols and utilize them for their own data set. In addition, web links are provided to the programs and tools discussed in several chapters. This 978-1-4757-8831-0978-0-306-47598-6

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Patrick McConnell,Kimberly Johnson,David J. Lockhartthe complex terrain which readers are invited to enter; or to direct the attention of potential readers to what the editors take to be the essential or central 978-0-387-97963-2978-1-4612-2746-5Series ISSN 1431-7532

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Joaquín Dopazothe complex terrain which readers are invited to enter; or to direct the attention of potential readers to what the editors take to be the essential or central 978-0-387-97963-2978-1-4612-2746-5Series ISSN 1431-7532

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