Titlebook: Methods of Cancer Diagnosis, Therapy, and Prognosis; General Overviews, H M. A. Hayat Book 2010 Springer Science+Business Media B.V. 2010 O

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Eiichi Morii,Katsuyuki Aozasand molecular physics, quantum chemistry, quantum fluids and plasmas, and solid-state and condensed matter physics. A special feature of the present meeting however was that particular attention was paid in the programme to such topics of current interest in solid-state physics as high-temperature su

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Role of RNA Interference in Understanding the Molecular Basis of Cancere antisense siRNAs to their respective target genes and induces mRNA cleavage or translational repression. Cleavage is enabled after an ATP-helicase unwinds the RNAi duplex and the degree of complementarity between the sequences determines the efficacy of binding. A significant sequence match will r

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Cancer Biomarkers (An Overview)tics of tissues. Because of the heterogeneity among diseases and patients, recharacteri­zation of cancer in pathophysiological terms via biomarker is a key to the future of medicine. Detection of cancer biomarkers can be accomplished by a wide variety of methods, ranging from biochemical anal­ysis o

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Chemotherapy-Induced Neurotoxicityarboplatin, oxaliplatin), taxanes (paclitaxel, docetaxel) and vinca alkaloids (vincristine). Other therapies such as suramin, thalidomide, and bortezomib can also produce significant neurotoxicity (Quasthoff and Hartung 2002; Hausheer et al. 2006). Previous or coincident administration of neurotoxic

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Translating In Vitro Cell Lines Result into Clinical Practiceesults. Some assays require large amount of material; with cell line models, this is generally not a constraint. Cells can be stored indefinitely in liquid nitrogen and can be used when needed. Apart from the ease in maintenance and access, cell lines offer a convenient platform for genetic manipula