Titlebook: Methods in Bone Biology; Timothy R. Arnett,Brian Henderson Book 1998 Springer Science+Business Media Dordrecht 1998 animals.biology.bone.c

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Book 1998Methods in Bone Biology is unique in being devoted todescribing the methodology used by bone researchers. This bookdescribes in detailthe techniques of cell and organ culture used inthe study of boneand bone cell function and the techniques used tomonitor theskeleton and skeletal remodelling both in clinical andexperimentalsettings.

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https://doi.org/10.1007/b102333animals; biology; bone; cell; cells; metabolism

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chniques of cell and organ culture used inthe study of boneand bone cell function and the techniques used tomonitor theskeleton and skeletal remodelling both in clinical andexperimentalsettings.978-1-4757-7122-0978-0-585-38227-2

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In vitro ,,es in adult primates, and osteoclasts that exist are difficult to harvest because they are situated on calcified bone surfaces within the medullary cavity. For these reasons the generation of osteoclasts from precursors using . models has been of major interest to those involved in studying the biol

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Methods for studying cell death in bone,d pathological settings. It has been defined by a series of characteristic morphological changes that take place in nuclear chromatin and cytoplasm of cells dying by a mechanism that differs from ischaemic necrosis in that it typically affects single cells, rather than groups of cells [., .], These

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Models for mechanical loading of hone and hone cells in vivo and in vitro,ces. When this requirement is not met, bones break. Since the disability associated with a broken bone affects the survival of an individual and therefore the species, there has been an evolutionary drive to minimize fracture incidence. Against this are the needs of efficiency, since an overengineer