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Titlebook: Metastasis of Breast Cancer; Robert E. Mansel,Oystein Fodstad,Wen G. Jiang Book 2007 Springer Science+Business Media B.V. 2007 BRCA.angiog

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Cell adhesion molecules in breast cancer invasion and metastasis,secondary site. Cell adhesion molecules including the cadherins, immunoglobulin superfamily, selectins, and integrins play important roles in tumor metastasis. Mucins can also be involved in tumor cell adhesion. In this chapter we review the current knowledge of these groups of cell adhesion molecules in breast cancer.
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BRCA1 in initiation, invasion, and metastasis of breast cancer: a perspective from the tumor microeal features of BRCA1-associated tumors remains elusive. Why do . mutations predominantly affect female breast and ovaries? Why do .-associated cancers tend to have a poor prognosis? How can the knowledge of BRCA1 function be translated into more targeted and efficacious therapies? In this review, we
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The insulin-like growth factor-1 ligand in breast cancer management, ligand expression in breast cancer tissue is not consistently associated with better or worst prognosis features. Identifying the IGF-1 gene polymorphism can potentially be used in predicting breast cancer risk and 17beta HSD 1 inhibitors is underway with promising initial results.
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