Titlebook: Metals in the Brain; Measurement and Imag Anthony R. White Book 2017 Springer Science+Business Media LLC 2017 Microscopy.fixation artifacts

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Monitoring Intracellular Zn2+ Using Fluorescent Sensors: Facts and Artifacts, these sensors can be categorized as low molecular weight probes or genetically encoded proteins. Based on the nature of the signal emitted by these sensors, they can be divided into two groups: (1) nonratiometric sensors whose fluorescence intensity reports [Zn.] and (2) ratiometric sensors, with [

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Introduction and Overview, and artifact-prone data. The chapters following this introduction will provide a broad and where necessary in-depth coverage of the leading approaches used today for assessment of metal levels in brain, brain-derived cells, and in some cases serum (which can be used to provide important collorary i

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X-Ray Microscopy for Detection of Metals in the Brain, undertake direct imaging of the metal elements in brain tissue. In this chapter we discuss the particular role of X-ray methods for imaging of accumulated metal species and metal-containing compounds in biological materials, particularly brain tissue. We discuss methods for synchrotron imaging of m

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Current Methods Used to Probe and Quantify Intracellular Total and Free Zn(II) Dynamics, and Subceln as well as methods that can detect and monitor the intracellular distribution and free concentration in the cytosol and various organelle compartments. In this chapter, the authors wish to bring the reader up-to-date on methods used to quantify levels and changes in intracellular concentrations of

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Monitoring Intracellular Zn2+ Using Fluorescent Sensors: Facts and Artifacts,ects and for this reason ratiometric sensors are preferable tools to monitor [Zn.].. Nevertheless, to interpret these data, critical analysis is necessary. In particular, calibration of the data in terms of [Zn.]. is problematic if the intracellular concentration of a sensor approaches or exceeds it

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Adam P. Gunn,Blaine R. Robertsequired in the practice of nuclear medicine, presented in a concise form for easy understanding and quick reference related to a given situation and/or incident. This is an ideal reference for nuclear medicine physicians, nuclear medicine technologists, and researchers using radioactive materials. .978-3-030-16406-5

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Raúl González-Domínguezequired in the practice of nuclear medicine, presented in a concise form for easy understanding and quick reference related to a given situation and/or incident. This is an ideal reference for nuclear medicine physicians, nuclear medicine technologists, and researchers using radioactive materials. .978-3-030-16406-5