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Titlebook: Metallothioneins in Normal and Cancer Cells; Piotr Dziegiel,Bartosz Pula,Marzenna Podhorska-Oko Book 2016 The Editor(s) (if applicable) an

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发表于 2025-3-21 18:10:21 | 显示全部楼层 |阅读模式
书目名称Metallothioneins in Normal and Cancer Cells
编辑Piotr Dziegiel,Bartosz Pula,Marzenna Podhorska-Oko
视频video
概述Illustrates the complete involvement of Metallothioneins in multiple biological processes.Explains how Metallothioneins play an important role in cell senescence progression.Clinical Application: High
丛书名称Advances in Anatomy, Embryology and Cell Biology
图书封面Titlebook: Metallothioneins in Normal and Cancer Cells;  Piotr Dziegiel,Bartosz Pula,Marzenna Podhorska-Oko Book 2016 The Editor(s) (if applicable) an
描述This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system. 
出版日期Book 2016
关键词cell senescence progression; intracellular zinc homeostasis; toxic metal detoxification; growth inhibi
版次1
doihttps://doi.org/10.1007/978-3-319-27472-0
isbn_softcover978-3-319-27471-3
isbn_ebook978-3-319-27472-0Series ISSN 0301-5556 Series E-ISSN 2192-7065
issn_series 0301-5556
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Metallothioneins: Structure and Functions,animal species. In mammals, a single MT molecule is made up of 61–68 amino acids, depending on the isoform (the MT-1, MT-2, and MT-4 isoforms consist of 61–62 amino acids, whereas the MT-3 isoform comprises 68 amino acids), and the protein sequence is composed of up to 20 cysteine (Cys) residues (Va
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Metallothionein-3, neuronal growth-inhibitory factor (GIF), still raises many questions (Uchida et al. 1991). The original name was derived from the initially discovered functions of this protein, i.e., its strong ability to impair neurite overgrowth and neural survival of cultured neurons. Further studies on the str
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Metallothioneins and Immune Function,(Chakrabarty and Maiti 1985). MTs were also detected in immune organs, including the spleen, the bone marrow, and the thymus (Savino et al. 1984; Huber and Cousins 1993). In the human thymus, MTs were found to colocalize with thymulin on the cellular level (Savino et al. 1984). The biological activi
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Piotr Dziegiel,Bartosz Pula,Christopher Kobierzycki,Mariusz Stasiolek,Marzenna Podhorska-Okolowe platform carried a variety of sensors; the Synthetic Aperture Radar (SAR) is widely cons- ered to be the most important. This active sensing technique provides all-day and all-weather mapping capability of considerably ?ne spatial resolution. ERS 1 and its sister system ERS 2 (launch 1995) were pr
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Piotr Dziegiel,Bartosz Pula,Christopher Kobierzycki,Mariusz Stasiolek,Marzenna Podhorska-Okolowe platform carried a variety of sensors; the Synthetic Aperture Radar (SAR) is widely cons- ered to be the most important. This active sensing technique provides all-day and all-weather mapping capability of considerably ?ne spatial resolution. ERS 1 and its sister system ERS 2 (launch 1995) were pr
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