书目名称 | Metal Ions in Neurological Systems |
编辑 | Wolfgang Linert,Henryk Kozlowski |
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概述 | Provides up to date knowledge about the effects of metal ions in the brain.Discusses the basic biology and pathological disorders.Focuses on selected topics dealing with the necessity and hams of meta |
图书封面 |  |
描述 | Metal ions in the brain are a necessity as well as a poison. The presence of metal ions in the active sites of biological catalysts or metalloproteins and in the biological functioning of nucleic acids is very well documented and they are required for brain activity. On the other hand, metals are very effective in generating oxidative stress. This effect does not only play a role in immunology but also is the root of practically all neurodegenerative disorders by inducing disease via the death of neurons. Managing metal ions in the brain could therefore be an important strategy in the search for therapeutic agents used in the treatment of neurodegenerative diseases. This new title gives an overview to key topics in the area of metal ions in the brain. It focuses on the role of metal ions in neurological systems by describing their advantageous functions as well as their poisonous features. It is therefore of interest for scientists in biochemistry and biophysics, physiology, toxicology as well as for physicians focused on this topic. |
出版日期 | Book 2012 |
关键词 | metal ions; metalloproteins; neurological systems |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-7091-1001-0 |
isbn_softcover | 978-3-7091-1678-4 |
isbn_ebook | 978-3-7091-1001-0 |
copyright | Springer-Verlag Wien 2012 |