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Titlebook: Metal Ions in Neurological Systems; Wolfgang Linert,Henryk Kozlowski Book 2012 Springer-Verlag Wien 2012 metal ions.metalloproteins.neuro

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Prion diseases and manganism,of iron ion in these enzymes with other metal ions such as manganese ion results in complete or partial loss of enzymatic activity, and this is because the reactivity of the iron ion towards oxygen molecule is quite different from that of the manganese ions. Thus, the excess accumulation of the mang
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,Aluminum increases toxic effects of amyloid β-peptides on the human erythrocyte membrane and molecuheir capacity to perturb the bilayer structures of DMPC and DMPE was assessed by X-ray diffraction, IUM were studied by fluorescence spectroscopy, and intact human erythrocytes were observed by scanning electron microscopy (SEM). It was found that Aβ(1–40) and Aβ(1–42) in the presence of Al(III) alt
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Heavy metals, behavior, and neurodegeneration: using , to untangle a can of worms,tion and mechanisms of toxicity of a wide range of toxicants. In this chapter, we provide an overview on the system model and discuss contemporary insights derived from . on the involvement of metals in behavior and neurodegenerative diseases.
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,The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106–1of the potentiometric and spectroscopic results revealed the stabilizing role of the oxygen donors of seryl, threonyl, or methoxyseryl residues of Ac-SKHM-NH., Ac-TKHM-NH., Ac-S(OMe)KHM-NH., and Ac-KTNSKHMAG-NH. containing the mutations in position 109. These interactions were, however, not observed
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ICP-MS for the neurodegenerative and brain sciences,s and bioimaging of metals in brain tissue samples, and protein analysis application with metals and ICP-MS. The subtopics of (1) isotope dilution analysis, (2) related immunoassay techniques, and (3) hyphenated instrumental applications are also presented. This chapter is meant to be a primer for a
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