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Titlebook: Metabolomics and Its Impact on Health and Diseases; Veronica Ghini,Kathleen A. Stringer,Claudio Luchin Book 2023 The Editor(s) (if applica

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NMR-Based Metabolomics to Evaluate Individual Response to Treatments,ty can be also monitored by metabolomics. We also show how the individual metabolomic fingerprint at the onset of a disease may discriminate responders from non-responders to a given drug, or how it may be prognostic of e.g., cancer recurrence after many years. In parallel with fingerprinting, profi
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Prospective Metabolomic Studies in Precision Medicine: The AKRIBEA Project,, using the Precision Medicine Initiative of the Basque Country (the AKRIBEA project) as a case study. To that end, we will illustrate the procedures to be followed when conducting an NMR-based metabolomics study with a large cohort of individuals, emphasizing the critical points. The chapter will c
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Metabolomics of Respiratory Diseases,microbiome, we discuss microbiome-derived metabolites that arise from the gut and lung in asthma and COPD that have mechanistic implications for these diseases. Recent literature has suggested that metabolomics analysis using nuclear magnetic resonance (NMR) and mass spectrometry (MS) approaches may
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Veronica Ghini,Kathleen A. Stringer,Claudio LuchinDemonstrates how to generate metabolomics data including lipidomics/lipoproteomics.Helps understand mechanistic underpinnings of adverse drug events.Covers applications of metabolomics for phenotyping
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