Titlebook: Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis; George G. Harrigan,Royston Goodacre Textbook 2003 Springe

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The Role of Metabolomics in Systems Biology,life sciences (International Human Genome Sequencing Consortium, 2001; Venter et al., 2001). In turn, the enormous degree of complexity inherent in genomic information has revealed the limitations of purely genomic investigation. Recent research has extended to the study of the proteome, defined as

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Bioactive Lipids in Reproductive Diseases,ospholipid bilayer. The phospholipid bilayer creates the permeability barrier of all cells and serves as a matrix for a large number of proteins involved in diverse cellular functions including cellular communication, replication, trafficking . Although devoid of any catalytic activity, the phosphol

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Dynamic Profiling and Canonical Modeling,ngs and begin to change them in a targeted fashion that offers us benefit, may it be in medicine, agriculture, biotechnology, or a responsible exploitation of the environment. The challenge is that we were not provided with a blueprint of the inner workings of organisms. We have very many observatio

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The Human Metabolome,ome is the set of all metabolites in a human. Whereas the science of genomics is based upon a genome, the science of metabolomics is grounded in a metabolome. To continue the genome/metabolome analogy, it should be apparent that any published human genome is a statistical approximation as it is deri

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Stable Isotope-Based Dynamic Metabolic Profiling in Disease and Health,nteractions among these components establish a rationale for integrating functional genomics, proteomics and metabolomics, as a means to study the complete intracellular signal processing apparatus that regulates metabolic adaptation, phenotype and ultimately cellular function (Kell and King, 2000).