| 书目名称 | Messenger RNA Therapeutics |
| 编辑 | Stefan Jurga,Jan Barciszewski |
| 视频video | |
| 概述 | Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics.Discusses the strengths and key challenges of this emerging class of drugs.Provides a state-of-the-art overview |
| 丛书名称 | RNA Technologies |
| 图书封面 |  |
| 描述 | This book focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. .This new book in the .RNA Technologies. series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic |
| 出版日期 | Book 2022 |
| 关键词 | mRNA therapeutics; RNA vaccines; SARS-CoV-2; Lipid nanoparticles; Adjuvants; Cancer Immunotherapy; Self-am |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-08415-7 |
| isbn_softcover | 978-3-031-08417-1 |
| isbn_ebook | 978-3-031-08415-7Series ISSN 2197-9731 Series E-ISSN 2197-9758 |
| issn_series | 2197-9731 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:00:26
