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Titlebook: Medication-Related Osteonecrosis of the Jaws; Bisphosphonates, Den Sven Otto Book 2015 Springer-Verlag Berlin Heidelberg 2015 BRONJ.Bisphos

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Pharmacological Aspects of Antiresorptive Drugs: Bisphosphonates and Denosumab,isorders including osteoporosis, metastatic bone disease and hypercalcemia of malignancy. Bisphosphonates are administered either orally or intravenously, while denosumab is injected subcutaneously. While bisphosphonates are not metabolized and have a strong affinity to the bone and a very long half
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Bisphosphonate and Denosumab Therapy: Fields of Application, preferred antiresorptive drug for malignant and nonmalignant diseases characterized by various kinds of bone loss. In general, bisphosphonates may be considered as treatment option for preserving bone mineral density in any disease accompanied by increased bone resorption, regardless of the pathoge
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Imaging Modalities and Characteristics in Medication-Related Osteonecrosis of the Jaw,eonecrosis of the jaws (MRONJ). Various radiographic signs may be seen on panoramic radiographs, cone-beam computed tomography (CBCT), or multislice CT (MSCT) like sclerosis, persisting alveolar sockets, and lack of bone filling in extractions sites, osteolysis, and sequestration. While panoramic ra
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Local and Microvascular Free Flaps in Patients with Medication-Related Osteonecrosis of the Jaw,orptive drug-induced osteonecrosis) is considered a therapy-resistant form of osteonecrosis. Despite this conservative and surgical treatment, regimens have been attempted and recommended in the years since it was first identified..The key points after surgical debridement of the exposed bone sites
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Adjuvant Treatment Options in the Management of Medication-Related Osteonecrosis of the Jaw,[.]. The first objective of MRONJ treatment is to alleviate pain, reduce infection and stabilise the progression of disease with the closure of bone exposure. Several authors reported in literature two opposite approaches: surgical and non-surgical treatment [.]. Non-invasive treatment options inclu
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New and Innovative Treatment Strategies for Medication-Related Osteonecrosis of the Jaw,sis of the jaw due to bisphosphonate intake. More recently, regenerative concepts using stem cells from different sources and growth factors have been introduced for the treatment of medication-related osteonecrosis of the jaws. These new and innovative concepts seem to be promising future options i
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