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Titlebook: Medication-Related Osteonecrosis of the Jaws; Bisphosphonates, Den Sven Otto Book 2015 Springer-Verlag Berlin Heidelberg 2015 BRONJ.Bisphos

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发表于 2025-3-21 16:20:38 | 显示全部楼层 |阅读模式
书目名称Medication-Related Osteonecrosis of the Jaws
副标题Bisphosphonates, Den
编辑Sven Otto
视频video
概述Coverage of all aspects of osteonecrosis of the jaw related to treatment with antiresorptive drugs especially bisphosphonates and denosumab.Practical guidelines for students and practitioners.First st
图书封面Titlebook: Medication-Related Osteonecrosis of the Jaws; Bisphosphonates, Den Sven Otto Book 2015 Springer-Verlag Berlin Heidelberg 2015 BRONJ.Bisphos
描述.Osteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs .This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists..
出版日期Book 2015
关键词BRONJ; Bisphosphonates; Denosumab; Implants; Malignant Diseases; Oral Surgery
版次1
doihttps://doi.org/10.1007/978-3-662-43733-9
isbn_softcover978-3-662-52433-6
isbn_ebook978-3-662-43733-9
copyrightSpringer-Verlag Berlin Heidelberg 2015
The information of publication is updating

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Dental Implants in the Context Antiresorptive Drugs and Medication-Related Osteonecrosis of the JawJ and can even help in rehabilitation after MRONJ. Furthermore, as antiresorptive medication and especially bisphosphonate medication is frequent, and need for implant is frequent, too, there is emerging question on indication of dental implants in these increasing patient groups.
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Epidemiology of Medication-Related Osteonecrosis of the Jaw,J/MRONJ with intravenous BP administration reached as high as 10 %, with the highest prevalence observed among multiple myeloma patients and the lowest prevalence measured among breast cancer patients.
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Microbiology and Antibiotics in the Context of Medication-Related Osteonecrosis of the Jaw,over the oral microbial bacteria and the bacteria expected in odontogenic infections. Additional factors have been discussed supporting the idea that bisphosphonates themselves attract bacteria at the bone as certain phyla and species could be found more frequently in osteonecrotic bone when compared to other infections.
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Animal Models of Medication-Related Osteonecrosis of the Jaw,L inhibitors. The establishment of these models will be essential in propelling the field forward to understand the underlying pathophysiology of ONJ and ultimately finding a way to prevent or cure this debilitating condition.
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Book 2015es and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs .This textbook provides
发表于 2025-3-23 03:28:03 | 显示全部楼层
History of Osteonecrosis of the Jaw,les concerning prevention and treatment were similar to those of our days. The Bern convention banned the use of yellow phosphorous. In the following decades, the disease gradually disappeared from common knowledge, until Robert Marx described the first modern bisphosphonate-related osteonecrosis of the jaw in 2003.
发表于 2025-3-23 07:55:25 | 显示全部楼层
Pharmacological Aspects of Antiresorptive Drugs: Bisphosphonates and Denosumab,ic bone disease as well as other bone disorders with great success. Generally, bisphosphonates and denosumab are well tolerated and have few side effects. However, both substance classes of osteotrop antiresorptives have one side effect in common, namely, osteonecrosis of the jaw.
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