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Titlebook: Mediators and Drugs in Gastrointestinal Motility II; Endogenous and Exoge Giulio Bertaccini (Head of the Department of Pharm Book 1982 Spri

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Peptides: Pancreatic Hormones,etic and physiologic significance (for reviews see . and . 1972; . et al. 1977). No wonder that their effects have so many points in common: both stimulate the secretion of insulin, inhibit gastric secretion, and exert a predominant inhibitory effect on gastrointestinal motility. This latter effect will be described in detail.
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Amines: Histamine,mber and susceptibility of receptors at the specific targets, the interaction with other humoral and nervous mediators, etc. Of course, detailed consideration of histamine distribution, synthesis, and metabolism is beyond the scope of this review.
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Peptides: Gastrointestinal Hormones,present in several forms because of its biosynthetic pathways and enzymatic degradation: a “big gastrin” with 34 amino acid residues (this is referred to as G 34), the heptadecapeptide “little gastrin,” (G 17), and a “minigastrin” isolated from gastrinoma tissue by . and . (1974) and thought initial
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Pharmacology of Adrenergic, Cholinergic, and Drugs Acting on Other Receptors in Gastrointestinal Muy (ECA) or pacemaker activity, on which are superimposed spikes or action potentials. Slow waves or ECA without spikes are not accompanied by contractile activity. Contractions are usually but not always accompanied by spikes; there may be massive depolarisation leading to inactivation of spike mech
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