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Titlebook: Mechanisms of Stimulus—Response Coupling in Platelets; J. Westwick,M. F. Scully,V. V. Kakkar Book 1985 The Editor(s) (if applicable) and T

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书目名称Mechanisms of Stimulus—Response Coupling in Platelets
编辑J. Westwick,M. F. Scully,V. V. Kakkar
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Mechanisms of Stimulus—Response Coupling in Platelets;  J. Westwick,M. F. Scully,V. V. Kakkar Book 1985 The Editor(s) (if applicable) and T
描述Since its inception the research area of platelet pharmacology has always been a vigorous one and it is a characteristic that new approaches to the understanding of platelet function are rapidly and thoroughly investigated. The intensity of this activity is attri­ butable, probably, to an appreciation by research workers in the field that a satisfactory therapeutic control of platelet function has yet to be realized. Also that if and when this problem of con­ trolling platelet function is achieved the benefits to clinical medicine will be immense since platelets are known to be involved in a multiplicity of events coupled within the haemostatic mechanisms and inflammatory responses. Aberrations in the behaviour of plate­ lets is part of the aetiology of atherosclerosis, myocardial and cerebral infarction and thrombosis. At this point in time, research in platelet function is in a particularly rapid state of flux. The recent findings of research workers active in the field and also workers investigating mechan­ isms of stimulus response coupling in other cells, have provided interesting insights into the generality of mechanisms involved in the function of responsive cells. One may
出版日期Book 1985
关键词Ether; Lipid; Nucleotid; Protein; behavior; cell; development; etiology; inflammatory response; medicine; oxyg
版次1
doihttps://doi.org/10.1007/978-1-4615-9442-0
isbn_softcover978-1-4615-9444-4
isbn_ebook978-1-4615-9442-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Characterisation of ADP Receptorsfibrinogen and, in the presence of sufficient calcium, to aggregate and release the contents of storage granules. These effects of ADP are competitively inhibited by the related nucleotides adenosine 5′-triphosphate (ATP) and adenosine 5′-monophosphate (AMP) which interact with the ADP receptor..
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